原 著：《 Preterm Labor and Delivery》译 著：《早产与分娩》

This splendid volume presents numerous aspects of preterm labor and delivery, from its fundamental mechanism to clinically focused approaches.

The incidence of preterm delivery is 6-7% in Japan, while globally up to 10% of pregnancies with preterm labor result in premature delivery. The rates of overall survival and intact survival of the premature infants are also excellent in Japan. Thus Japan’s approach to preterm labor and delivery has long attracted attention. In each chapter, experts describe specific issues unique to conditions in Japan, including diagnosis, tocolytic agents, definition of clinical chorioamnionitis, treatment of bacterial vaginosis, role of amniocentesis, management of preterm premature membrane rupture and also placental pathology, presenting definitive evidence of the reduced incidence of preterm delivery in Japan.

This book benefits not only obstetricians, pediatricians and gynecologist, but also midwives, nurse practitioners, and medical and associated staffs in the field of obstetrics, pediatrics, as well as neonatal and perinatal medicine who are involved in delivery.

1. Impacts on Perinatal Ecology

2. Definition and Diagnosis of Preterm Labor 

3. Epidemiology and Incidence of Preterm Delivery 

4. Subclinical Intrauterine Infection 

5. Clinical and Subclinical Intrauterine Infection or Inflammation 

6. Cervical Changes 1: Morphological and Biochemical Changes 

7. Cervical Changes 2: USG Findings 

8. Multiple Mechanisms of Preterm Labor Other Than Intrauterine Infection 

9. Abruption and Preterm Labor 

10. Prevention and Tocolytic Agent: Hydration, Bed Rest, Ritodrine, and Special Comments on Long-Term Tocolysis 

11. Prevention and Tocolytic Agents 2 

12. Maintenance Tocolytic Therapy 

13. Antibiotics for Preterm Labor 

14. Probiotics for Preterm Labor

15. Progesterone 

16. Cerclage 1: General 

17. Cerclage 2: Abdominal vs Vaginal 

18. Bacterial Vaginosis 

19. Antenatal Corticosteroid 

20. Preterm Birth and Mode of Delivery 

21. Premature Rupture of Membranes 

22. The Preterm Newborn: Morbidity and Mortality—Including a Population-Based Study in Miyazaki Prefecture 

23. Placental Pathology 

24. Genetic Analysis of Spontaneous Preterm Birth